Patologías del niño inmigrante en la Unidad de Cuidados Intensivos: actualización / Pathologies of the immigrant child in the Intensive Care Unit: update

Resumen: Cada vez es más frecuente la atención médica en la Unidad de Cuidados Intensivos (UCI) de niños o adolescentes inmigrantes como también de aquellos nacidos en nuestro país con padres en tal condición. Esto ha ocasionado, en la actualidad, que el equipo de salud se deba enfrentar con problemas diagnósticos derivados del escaso conocimiento de condiciones genéticas propias de esta población y/o el desarrollo de diversas patologías infrecuentes en nuestro país, algunas resultantes de su condi ción sanitaria. En esta revisión se abordan diversos aspectos de la patología hematológica, infecciosa, parasitaria, respiratoria y cardiovascular, todos tópicos relevantes de conocer durante su estadía en la UCI. Es un deber del equipo de salud actualizarse sobre patologías de baja prevalencia en nuestro país, algunas de ellas muy poco conocidas hasta hace una década, pero que, actualmente, están cada vez más presentes en las UCI del sistema de salud público chileno.

Abstract: It is increasingly common to provide medical care in the Intensive Care Unit (ICU) for immigrant children and adolescents as well as those born in Chile with parents in such condition. Currently, this has caused that the health team has to face diverse infrequent pathologies in our country and/ or diagnostic problems derive from the poor knowledge of genetic conditions of this population, some resulting from their health conditions. This review addresses several aspects of hematological, infectious, parasitic, respiratory, and cardiovascular pathologies, all relevant topics to know during their stay in the ICU. It is a duty of the health team to be updated on pathologies of low prevalence in our country, some of them very little known until a decade ago, but which are currently increasingly present in the ICUs of the Chilean public health system.

Factores de riesgo cardiovascular en Estados Unidos y México: comparación de los estudios HABLE y ENASEM / Cardiovascular risk factors in Mexico and the United States: a comparative cross-sectional study between the HABLE and MHAS participants

Resumen Introducción: En Estados Unidos se dispone de información acerca de la población mexicoamericana por el Estudio de Salud y Envejecimiento del Cerebro en Latinos Mayores (HABLE); en México se dispone de los resultados del Estudio Nacional de Salud y Envejecimiento en México (ENASEM). Objetivo: Comparar la prevalencia de factores de riesgo cardiovascular entre hombres y mujeres de HABLE y ENASEM. Método: Se analizó transversalmente la prevalencia de hipertensión, diabetes, hipercolesterolemia y obesidad abdominal en 559 participantes de HABLE y se comparó con datos de 13 663 participantes del ENASEM. La comparación se realizó mediante t de Student y chi cuadrada, según el tipo de variable. Resultados: El análisis demostró que la prevalencia de hipertensión (50 %, IC 95 % = 41.8-51.8), diabetes (35.5 %, IC 95 % = 27.6-43.8) y obesidad abdominal (59.3 %, IC 95 % = 50.5-68.1) fueron significativamente mayores en hombres del HABLE, mientras que las mujeres presentaron una prevalencia más elevada de diabetes (36.8 %, IC 95 % = 32.2-41.5) y obesidad abdominal (89.6 %, IC 95 % = 86.6-92.5). La hipercolesterolemia tuvo una prevalencia más elevada en mujeres del ENASEM (53.3 %, IC 95 % = 50.3-56.2). Conclusión: La prevalencia de factores de riesgo cardiovascular fue mayor en mexicoamericanos participantes del HABLE, que en mexicanos participantes del ENASEM.

Abstract Introduction: In the United States, information on the Mexican-American population is available through the Health and Aging Brain among Latino Elders (HABLE) study; in Mexico, the results of the Mexican Health and Aging Study (MHAS) are available. Objective: To compare the prevalence of cardiovascular risk factors between men and women of the HABLE and MHAS studies. Method: The prevalence of hypertension, diabetes, hypercholesterolemia and abdominal obesity was transversely analyzed in 559 HABLE participants and compared with data from 13,663 MHAS participants. The comparison was made using Student’s t-test and the chi-square test, according to the type of variable. Results: The analysis showed that the prevalence of hypertension (50 %, 95 % CI = 41.8-51.8), diabetes (35.5 %, 95 % CI = 27.6-43.8) and abdominal obesity (59.3 %, 95 % CI = 50.5-68.1) were significantly higher in HABLE males, whereas females had a higher prevalence of diabetes (36.8 %, 95 % CI = 32.2-41.5) and abdominal obesity (89.6 %, 95 % CI = 86.6-92.5). Hypercholesterolemia had a higher prevalence in MHAS females (53.3%, 95% CI = 50.3-56.2). Conclusion: The prevalence of cardiovascular risk factors was higher in Mexican American HABLE participants, than in Mexican MHAS participants.

Síndrome metabólica: análise conceitual no contexto da enfermagem / Metabolic Syndrome: conceptual analysis in the nursing context / Síndrome metabólica: análisis conceptual en el contexto de la enfermería

Objetivo analisar o conceito síndrome metabólica e identificar respectivos atributos essenciais, antecedentes e consequentes no contexto da enfermagem. Método análise conceitual, a partir dos passos metodológicos de um modelo. Realizou-se revisão integrativa, por meio de acesso on-line a quatro bases de dados: Medical Literature Analysis and Retrieval System Online, Scientific Electronic Library Online, Literatura Latino-Americana em Ciências da Saúde e Índice Bibliográfico Español en Ciencias de la Salud. Resultados os atributos essenciais mais frequentes envolveram os critérios diagnósticos da síndrome metabólica. Alimentação inadequada e sedentarismo destacaram-se como antecedentes mais comuns da síndrome, e os consequentes foram ocorrências de doenças cardiovasculares e diabetes mellitus tipo 2. Como implicação, tem-se o destaque de relevantes dados empíricos para definição ampla do conceito. Conclusão foi possível analisar o conceito em estudo no que concerne aos atributos essenciais, antecedentes e consequentes, definindo-o operacionalmente como potencial fenômeno de enfermagem que demanda cuidados direcionados para redução do risco e da morbimortalidade por doenças cardiovasculares.

Objective to analyze the metabolic syndrome concept and to identify its essential features, antecedents, and outcomes within the context of nursing. Method conceptual analysis, based on the methodological steps of a model. We carried out an integrative review by accessing four databases online: Medical Literature Analysis and Retrieval System Online, Scientific Electronic Library Online, Latin American and Caribbean Health Sciences Literature, and Índice Bibliográfico Español en Ciencias de la Salud. Results the essential features most frequently involved the diagnostic criteria of metabolic syndrome. Inadequate nutrition and physical inactivity were highlighted as the most common antecedents of the syndrome, and the outcomes were occurrences of cardiovascular disease and diabetes mellitus type 2. As implication, we highlight relevant empirical data to the broad definition of the concept. Conclusion we could analyze the concept under study regarding essential features, antecedents, and outcomes, operationally defining it as a potential nursing phenomenon, which demands health care focusing on reducing risks and morbidity and mortality for cardiovascular diseases.

Objetivo analizar el concepto síndrome metabólica e identificar respectivos atributos esenciales, antecedentes y consecuentes en el contexto de la enfermería. Método análisis conceptual, desde los pasos metodológicos de un modelo. Se realizó la revisión integrativa, por medio de acceso online a cuatro bases de datos: Medical Literature Analysis and Retrieval System Online, Scientific Electronic Library Online, Literatura Latinoamericana en Ciencias de la Salud y Índice Bibliográfico Español en Ciencias de la Salud. Resultados los atributos esenciales más frecuentes involucraron los criterios diagnósticos del síndrome metabólica. Alimentación inadecuada y sedentarismo se destacaron como antecedentes más comunes del síndrome, y los consecuentes fueron ocurrencias de enfermedades cardiovasculares y diabetes mellitus tipo 2. Como implicación, se tiene el destaque de relevantes datos empíricos para la definición amplia del concepto. Conclusión ha sido posible analizar el concepto en estudio en el que concierne a los atributos esenciales, antecedentes y consecuentes, definiéndolo operacionalmente como potencial fenómeno de enfermería que demanda cuidados direccionados para la reducción del riesgo y de la morbimortalidad por enfermedades cardiovasculares.

Cardiovascular Risk in Xavante Indigenous Population / Risco Cardiovascular na População Indígena Xavante

Abstract Background: The prevalence of cardiovascular risk factors is little known in Brazilian indigenous populations. In the last two decades, important changes have occurred in the lifestyle and epidemiological profile of the Xavante people. Objective: to assess the prevalence of cardiovascular risk factors in Xavante adults in São Marcos and Sangradouro/Volta Grande reserves, in the state of Mato Grosso, Brazil. Methods: Cross-sectional study carried out with 925 Xavante people aged ≥ 20 years between 2008 and 2012. The following indicators were assessed: triglycerides (TG), total, LDL and HDL-cholesterol, Castelli index I and II, TG/HDL-cholesterol ratio, apo B / Apo A1 ratio, Framingham risk score, C-reactive protein, body mass index (BMI), waist circumference (WC), hypertriglyceridemic waist (HW), glycemia and blood pressure. Kolmogorov-Smirnov, Student's t test and Chi-square test (χ2) were used for statistical analysis, and significance level was set at 5%. Results: High prevalence of elevated cardiovascular risk was observed in men and women according to HDL-cholesterol (66.2% and 86.2%, respectively), TG (53.2% and 51.5%), TG/HDL-cholesterol ratio (60.0% and 49.1%), C-reactive protein (44.1% and 48.1%), BMI (81.3% and 81.7%), WC (59.1% and 96.2%), HW (38.0% and 50,6%) and glycemia (46.8% and 70.2%). Individuals aged 40 to 59 years had the highest cardiovascular risk. Conclusions: The Xavante have a high cardiovascular risk according to several indicators evaluated. The present analysis of cardiovascular risk factors provides support for the development of preventive measures and early treatment, in attempt to minimize the impact of cardiovascular diseases on this population.

Resumo Fundamento: A prevalência de fatores de risco cardiovascular ainda é pouco estudada em populações indígenas brasileiras. Nas duas últimas décadas, observaram- se importantes mudanças no estilo de vida e no perfil epidemiológico dos Xavante. Objetivo: Avaliar a prevalência de fatores de risco cardiovascular na população adulta Xavante das Reservas Indígenas de São Marcos e Sangradouro/Volta Grande - MT. Métodos: Estudo transversal realizado com 925 indígenas Xavante com 20 ou mais anos de idade, no período de 2008 a 2012. Foram considerados os indicadores: níveis séricos de triglicérides (TG), colesterol (total, LDL e HDL), Índices de Castelli I (CT/HDL-c) e II (LDL-c/HDL-c), razão TG/HDL-C, relação Apo B/Apo A1, escore de Framingham, proteína C reativa (PCR), Índice de Massa Corporal (IMC), circunferência da cintura (CC), cintura hipertrigliceridêmica (CH), glicemia e pressão arterial. Foram utilizados os testes Kolmogorov-Smirnov, t de Student e Qui quadrado (χ2), sendo considerado um nível de significância de 5%. Resultados: Verificaram-se altas prevalências de risco cardiovascular elevado, em homens e mulheres, respectivamente, segundo os indicadores HDL-colesterol (66,2% e 86,2%), TG (53,2% e 51,5%), razão TG/HDL-c (60,0% e 49,1%), PCR (44,1% e 48,1%), IMC (81,3% e 81,7%), CC (59,1% e 96,2%), CH (38,0% e 50,6%) e glicemia (46,8% e 70,2%). Os indivíduos de 40 a 59 anos foram os que apresentaram maior risco cardiovascular. Conclusões: Os Xavante apresentam elevado risco cardiovascular segundo vários indicadores avaliados. Este inquérito fornece subsídios para ações de prevenção e tratamento precoce, a fim de minimizar os potenciais danos causados por doenças cardiovasculares entre os Xavante.

Urbanization is Associated with Increased Trends in Cardiovascular Mortality Among Indigenous Populations: the PAI Study / Urbanização Associa-se com Tendência a Maior Mortalidade Cardiovascular em Populações Indígenas: o Estudo PAI

Abstract Background: The cardiovascular risk burden among diverse indigenous populations is not totally known and may be influenced by lifestyle changes related to the urbanization process. Objectives: To investigate the cardiovascular (CV) mortality profile of indigenous populations during a rapid urbanization process largely influenced by governmental infrastructure interventions in Northeast Brazil. Methods: We assessed the mortality of indigenous populations (≥ 30 y/o) from 2007 to 2011 in Northeast Brazil (Bahia and Pernambuco states). Cardiovascular mortality was considered if the cause of death was in the ICD-10 CV disease group or if registered as sudden death. The indigenous populations were then divided into two groups according to the degree of urbanization based on anthropological criteria:9,10 Group 1 - less urbanized tribes (Funi-ô, Pankararu, Kiriri, and Pankararé); and Group 2 - more urbanized tribes (Tuxá, Truká, and Tumbalalá). Mortality rates of highly urbanized cities (Petrolina and Juazeiro) in the proximity of indigenous areas were also evaluated. The analysis explored trends in the percentage of CV mortality for each studied population. Statistical significance was established for p value < 0.05. Results: There were 1,333 indigenous deaths in tribes of Bahia and Pernambuco (2007-2011): 281 in Group 1 (1.8% of the 2012 group population) and 73 in Group 2 (3.7% of the 2012 group population), CV mortality of 24% and 37%, respectively (p = 0.02). In 2007-2009, there were 133 deaths in Group 1 and 44 in Group 2, CV mortality of 23% and 34%, respectively. In 2009-2010, there were 148 deaths in Group 1 and 29 in Group 2, CV mortality of 25% and 41%, respectively. Conclusions: Urbanization appears to influence increases in CV mortality of indigenous peoples living in traditional tribes. Lifestyle and environmental changes due to urbanization added to suboptimal health care may increase CV risk in this population.

Resumo Fundamento: O risco cardiovascular das diversas comunidades indígenas não está bem estabelecido e pode ser influenciado pelo processo de urbanização a que se submetem esses povos. Objetivos: Investigar o perfil da mortalidade cardiovascular (CV) das populações indígenas durante o rápido processo de urbanização altamente influenciado por intervenções governamentais de infraestrutura no Nordeste do Brasil. Métodos: Avaliamos a mortalidade de populações indígenas (≥ 30 anos) do Vale do São Francisco (Bahia e Pernambuco) no período de 2007-2011. Considerou-se mortalidade CV se a causa de morte constasse no grupo de doenças CV do CID-10 ou se tivesse sido registrada como morte súbita. As populações indígenas foram divididas em dois grupos conforme o grau de urbanização baseado em critérios antropológicos: Grupo 1 - menos urbanizadas (Funi-ô, Pankararu, Kiriri e Pankararé); e Grupo 2 - mais urbanizadas (Tuxá, Truká e Tumbalalá). Taxas de mortalidade de cidades altamente urbanizadas (Petrolina e Juazeiro) nas proximidades das áreas indígenas foram também avaliadas. A análise explorou tendências na porcentagem de mortalidade CV para cada população estudada. Adotou-se o valor de p < 0,05 como significância estatística. Resultados: Houve 1.333 mortes indígenas nas tribos da Bahia e de Pernambuco (2007-2011): 281 no Grupo 1 (1,8% da população de 2012) e 73 no Grupo 2 (3,7% da população de 2012), mortalidade CV de 24% e 37%, respectivamente (p = 0,02). Entre 2007 e 2009, houve 133 mortes no Grupo 1 e 44 no Grupo 2, mortalidade CV de 23% e 34%, respectivamente. Entre 2009 e 2010, houve 148 mortes no Grupo 1 e 29 no Grupo 2, mortalidade CV de 25% e 41%, respectivamente. Conclusões: A urbanização parece influenciar os aumentos de mortalidade CV dos povos indígenas vivendo de modo tradicional. Mudanças no estilo de vida e ambientais devidas à urbanização somadas à subótima atenção à saúde podem estar implicadas no aumento do risco CV nos povos indígenas.

High-Sensitivity C-Reactive Protein and Cardiovascular Disease Across Countries and Ethnicities

Despite substantial differences in ethnicities, habits, cultures, the prevalence of traditional cardiovascular risk factors and affordable therapies, atherosclerosis remains the major cause of death in developing and developed countries. However, irrespective of these differences, inflammation is currently recognized as the common pathway for the major complications of atherosclerosis, stroke, and ischemic heart disease. A PubMed search was conducted for “high-sensitivity C-reactive protein” (hs-CRP) in combination with the terms race, ethnicity, gender, prevalence, geographic, epidemiology, cardiovascular, obesity, diabetes, hypertension, cholesterol, smoking, ischemic heart disease, stroke, and mortality. This review includes the articles that pertained to the topic and additional articles identified from the reference lists of relevant publications. This review describes the marked differences in cardiovascular mortality across countries and ethnicities, which may be attributed to inequalities in the prevalence of the classic risk factors and the stage of cardiovascular epidemiological transition. However, hs-CRP appears to contribute to the prognostic information regarding cardiovascular risk and mortality even after multiple adjustments. Considering the perception of cardiovascular disease as an inflammatory disease, the more widespread use of hs-CRP appears to represent a valid tool to identify people at risk, independent of their ancestry or geographic region. In conclusion, this review reports that the complications associated with vulnerable atherosclerotic plaques are triggered by the major mechanisms of dyslipidemia and inflammation; whereas both mechanisms are influenced by classic risk factors, hs-CRP contributes additional information regarding cardiovascular events and mortality.

Prevalencia de factores de riesgocardiovascular en comunidades pehuenches, Chile / Prevalence of the cardiovascular risk factors in a Pehuenches community, Chile

Introducción: la enfermedad cardiovascular constituye un problema de importancia en salud pública. El objetivo de este trabajo es determinar la prevalencia de factores de riesgo cardiovascular y su asociación con determinantes sociodemográficos, étnicos y clínicos en población de comunidades indígenas pehuenches en Chile. Métodos: estudio de corte transversal para determinar la prevalencia de factores de riesgo cardiovascular en población mayor de 15 años que habita en las comunidades pehuenches de Alto Biobio, en Chile, con una muestra de 400 individuos. Para la recolección de la información se utilizaron la normativa y criterios del Ministerio de Salud de Chile y la función de Framingham, la que fue tabulada en una planilla electrónica y analizada con el paquete estadístico STATA 10/SE. Resultados: la prevalencia de factores de riesgo cardiovascular fue: tabaquismo de 18,2 por ciento en hombres y 9,9 por ciento en mujeres; hipertensión arterial, 25,7 por ciento en hombres y 17,4 por ciento en mujeres; hipercolesterolemia, 9,1 por ciento en hombres y 8,4 por ciento en mujeres; y diabetes mellitus, 2,14 por ciento en hombres y 1,41 por ciento en mujeres. Se hallaron diferencias estadísticamente significativas con mayor prevalencia de factores de riesgo cardiovascular en hombres, población occidental y de mayor edad. Conclusión: el presente estudio mostró una elevada prevalencia, siendo superior en varones y en edades avanzada, y que los indígenas constituyen un grupo de menor riesgo para el desarrollo de enfermedades cardiovasculares, lo que podría cambiar producto de la occidentalización de los estilos de vida.

Introduction: cardiovascular disease is an important problem in public health. The aim of this work is determining the prevalence of the cardiovascular risk factors and their association with socio-demographic, ethnical and clinical determinants in populations of Pehuenches indigenous communities in Chile. Methods: cross-sectional study to determine the prevalence of cardiovascular risk factors in a population elder 15 years old living in the Pehuenches communities of Alto Biobio in Chile, using a sample of 400 persons. For collecting information we used method and criteria of the Chile Ministry of Health and Framingham function, tabulated in an electronic form and analyzed using the statistic pack STATA 10/SE. Results: the prevalence of the cardiovascular risk factors was: smoking 18, 2 % in men and 9,9 percent in women; arterial hypertension 25,7 percent in men and 17,4 percent in women; hyper cholesterolemy 9,1 percent in men and 8,4 percent in women and diabetes mellitus 2,14 percent in men and 1,41 percent in women. We found significant statistic differences with higher cardiovascular risk factors prevalence in men, western population and elder age. Conclusion: current research showed a high prevalence, being higher in male, elder people, highlighting that indigenous people is a group with lesser risk for developing cardiovascular diseases, what might change due to the westernization of the life styles.

Measuring progress of collaborative action in a community health effort / Medición del progreso de las actividades de colaboración en una iniciativa de salud comunitaria

OBJECTIVE: To measure the progress made by the collaborative actions of multisectorial partners in a community health effort using a systematic method to document and evaluate community/system changes over time. METHODS: This was a community-based participatory research project engaging community partners of the Latino Health for All Coalition, which based on the Health for All model, addresses health inequity in a low-income neighborhood in Kansas City, Kansas, United States of America. Guided by three research questions regarding the extent to which the Coalition catalyzed change, intensity of change, and how to visually display change, data were collected on community/system changes implemented by the community partners from 2009-2012. These changes were characterized and rated according to intensity (event duration, population reach, and strategy) and by other categories, such as social determinant of health mechanism and sector. RESULTS: During the 4-year study period, the Coalition implemented 64 community/system changes. These changes were aligned with the Coalition's primary goals of healthy nutrition, physical activity, and access to health screenings. Community/system efforts improved over time, becoming longer in duration and reaching more of the population. CONCLUSIONS: Although evidence of its predictive validity awaits further research, this method for documenting and characterizing community/system changes enables community partners to see progress made by their health initiatives.

OBJETIVO:Medir el progreso alcanzado por las actividades de colaboración de los socios multisectoriales en una iniciativa de salud comunitaria mediante el empleo de un método sistemático para verificar y evaluar los cambios en la comunidad y los sistemas con el transcurso del tiempo. MÉTODOS: Se trata de un proyecto comunitario de investigación participativa en el que colaboraron los socios comunitarios de la Coalición Salud para Todos los Latinos, que, con base en el modelo de Salud para Todos, aborda las desigualdades en materia de salud en un vecindario de bajos ingresos de Kansas City, en el estado de Kansas (Estados Unidos). Adoptando como guía tres preguntas de investigación referentes a en qué medida la Coalición catalizó los cambios, qué intensidad alcanzaron y cómo mostrarlos gráficamente, se recogieron datos sobre los cambios en la comunidad y los sistemas introducidos por los socios comunitarios del 2009 al 2012. Estos cambios se describieron y evaluaron según su intensidad (la duración del acontecimiento, el porcentaje de población expuesta y la estrategia) y según otras categorías, tales como el mecanismo implicado como determinante social de la salud y el sector afectado. RESULTADOS: Durante el período de estudio de cuatro años, la Coalición había introducido 64 cambios en la comunidad y los sistemas. Estos cambios estaban alineados con las principales metas de la Coalición: nutrición sana, ejercicio físico y acceso a los tamizajes de salud. Las iniciativas de la comunidad y los sistemas mejoraron con el transcurso del tiempo, eran más duraderas y llegaban a una parte más importante de la población. CONCLUSIONES:Aunque se requieren investigaciones adicionales para establecer datos probatorios de su validez predictiva, este método para verificar y caracterizar los cambios en la comunidad y los sistemas permite a los socios comunitarios observar el progreso alcanzado por sus iniciativas en pro de la de salud.

Cardiovascular risk in Japanese-Brazilian subjects / Risco cardiovascular em nipobrasileiros

OBJECTIVE: To evaluate the prevalence of risk factors for cardiovascular disease in Japanese-Brazilian subjects. SUBJECTS AND METHODS: One hundred thirty-one residents of the Mombuca community were studied. Statistical analysis was based on the X² test, Fisher's Exact test, Student's t test, and ANOVA, at a 5% significance level. RESULTS: The average age was 56.7 years-old; 76.3% had dyslipidemia, 24.4% pre-diabetes (PDM), 10.7% type 2 diabetes mellitus (T2DM), 46.6% hypertension, 52.7% abdominal obesity, and 35.8% metabolic syndrome (MS). There were significant correlations between HOMA-IR and MS diagnosis and obesity, while HOMA-β levels were decreased in T2DM and PDM. The ankle-brachial index was positive for peripheral artery disease in 22.3% of the individuals. Electrocardiograms did not show increased evidence of myocardial ischemia. CONCLUSION: Subjects of this community are exposed to major cardiovascular risk factors, namely high prevalence of MS diagnoses and increased HOMA-IR. Arq Bras Endocrinol Metab. 2012;56(9):608-13.

OBJETIVO: Avaliar a presença de fatores de risco para doença cardiovascular em nipo-brasileiros. SUJEITOS E MÉTODOS: Foram estudados 131 moradores de Mombuca. Utilizaram-se os testes do Qui-quadrado, Exato de Fisher, t de Student e ANOVA, com significância de 5%. RESULTADOS: A média de idade foi de 56,7 anos; 76,3% tinham dislipidemia, 24,4% pré-diabetes (PDM), 10,7% diabetes melito tipo 2 (DM2), 46,6% hipertensão, 52,7% obesidade abdominal e 35,8% síndrome metabólica (SM). Houve correlação significativa do HOMA-IR com SM e obesidade, enquanto HOMA-β esteve reduzido na presença de DM2 e PDM. O índice tornozelo-braquial foi positivo para doença arterial periférica em 22,3% dos indivíduos. O eletrocardiograma não mostrou aumento de isquemia miocárdica. CONCLUSÃO: A comunidade está exposta aos fatores de risco maiores para doença cardiovascular, o que pode ser resumido pela alta prevalência de diagnóstico de SM e valores elevados de HOMA-IR. Arq Bras Endocrinol Metab. 2012;56(9):608-13.

Encuesta de percepción de la enfermedad cardiovascular de la mujer por la mujer / Perception survey of cardiovascular disease for women by women

Antecedentes: las enfermedades del sistema circulatorio siguen siendo la primera causa de muerte en ambos sexos en Uruguay, no exisitiendo clara conciencia de ello. El objetivo de la encuesta fue evaluar la conciencia, percepción y conocimiento de la enfermedad cardiovascular (ECV) de la mujer, por la mujer. Método y resultado: se encuestaron 131 mujeres seleccionadas al azar, funcionarias no médicas ni enfermeras, de tres centros hospitalarios entre 1 de marzo y 15 de abril de 2012, con un cuestionario destinado a evaluar la percepción de la ECV como problema de salud y causa de muerte. La edad media fue 42 ± 12 años. El cáncer fue percibido como uno de los tres problemas más importantes de salud en 86%, seguido por la ECV en 33%. Con respecto a las tres causas más frecuentes de muerte, 63% nombró al cáncer en general, 54% muerte violenta, 49% cáncer de mama, 42% enfermedades cardíacas y 18% ataque cerebral. Solo 20,7% consideró que las enfermedades del corazón, son la primera causa de muerte en la mujeres, no observándose diferencias significativas en esta proporción de acuerdo al nivel de instrucción (chi cuadrado 0,48, p=0,92).La mayoría de las mujeres encuestadas (97%) acudieron a control médico en los últimos dos años, pero solo un tercio recibió información sobre la ECV y su prevención. Conclusiones: la percepción de las mujeres encuestadas es que el cáncer es el principal problema de salud y causa demuerte en su género; sólo 1 de cada 5 adjudicó a la ECV como la primera causa de muerte. Si bien la mujer conoce los síntomas, conoce menos los factores de riesgo y las conductas que reducen la ECV.

Cardiovascular disease still is the main cause of death in both men and women in Uruguay but this fact is ignored by most women. It is also vastly ignored by women belonging to western countries. The objective of this study is to evaluate the knowledge and perception of cardiovascular diseases of women by women.Method and results: 131 women were randomly selected in three hospitals between March 1 and April 4, 2012. Doctors and nurses were excluded. They answered a questionnaire that was prepared to evaluate the perception of cardiovascular disease as a health problem and cause of death in women. Mean age of the selected population was 42 ± 12 years. Cancer was perceived as one of the three more important health problems by 86% of the population, followed by heart diseases in 33%. When women in this group were asked for the three most frequent causes of death, 63% mentioned cancer in general, 54% mentioned violent death, 49% breast cancer, 42% cardiac diseases and 18% stroke. Only 20.7% of the selected group considered heart attack as first cause of death, there were no significant difference of proportions between different level of education groups (p=0,92). Ninety seven percent of the surveyed women had gone to see a doctor for health control in the last two years, but only one third of them received information about cardiovascular diseases and its prevention.Conclusion: the perception of the surveyed women is that cancer is their main health problem and cause of death. Just 1 of 5 considered cardiovascular disease as the main cause of death. In spite women were aware of the symptoms of cardiovascular disease, their knowledge of risk factors and their prevention is far less known.

A behavioral intervention in a cohort of Japanese-Brazilians at high cardiometabolic risk / Intervenção comportamental em nipo-brasileiros com alto risco cardiometabólico

OBJECTIVE: To assess the effect of a health promotion program on cardiometabolic risk profile in Japanese-Brazilians. METHODS: A total of 466 subjects from a study on diabetes prevalence conducted in the city of Bauru, southeastern Brazil, in 2000 completed a 1-year intervention program (2005-2006) based on healthy diet counseling and physical activity. Changes in blood pressure and metabolic parameters in the 2005-2006 period were compared with annual changes in these same variables in the 2000-2005 period. RESULTS: During the intervention, there were greater annual reductions in mean (SD) waist circumference [-0.5(3.8) vs. 1.2(1.2) cm per year, p<0.001], systolic blood pressure [-4.6(17.9) vs. 1.8(4.3) mmHg per year, p<0.001], 2-hour plasma glucose [-1.2(2.1) vs. -0.2(0.6) mmol/L per year, p<0.001], LDL-cholesterol [-0.3(0.9) vs. -0.1(0.2) mmol/L per year, p<0.001] and Framingham coronary heart disease risk score [-0.25(3.03) vs. 0.11(0.66) per year, p=0.02] but not in triglycerides [0.2(1.6) vs. 0.1(0.42) mmol/L per year, p<0.001], and fasting insulin level [1.2(5.8) vs. -0.7(2.2) IU/mL per year, p<0.001] compared with the pre-intervention period. Significant reductions in the prevalence of impaired fasting glucose/impaired glucose tolerance and diabetes were seen during the intervention (from 58.4% to 35.4%, p<0.001; and from 30.1% to 21.7%, p= 0.004, respectively). CONCLUSIONS: A one-year community-based health promotion program brings cardiometabolic benefits in a high-risk population of Japanese-Brazilians.

OBJETIVO: Avaliar o efeito do programa de promoção de saúde no perfil de risco cardiometabólico de nipobrasileiros. MÉTODOS: Um total de 466 participantes de estudo de prevalência de diabetes em Bauru, SP, no ano de 2000 completou um programa de intervenção de um ano (2005-2006) baseado em aconselhamento sobre dieta saudável e prática de atividade física. Alterações em pressão arterial e parâmetros metabólicos entre 2005 e 2006 foram comparados com alterações anuais nessas mesmas variáveis entre 2000 e 2005. RESULTADOS: Durante a intervenção, foram observadas maiores reduções anuais médias (dp) na circunferência da cintura [-0,5(3,8) vs. 1,2(1,2) cm/ano, p < 0,001], pressão arterial sistólica [-4,6(17,9) vs. 1,8(4,3) mmHg/ano, p < 0,001], glicemia 2h pós-sobrecarga de glicose [-1,2(2,1) vs. -0,2(0,6) mmol/L/ano, p < 0,001], LDL-c [-0,3(0,9) vs. -0,1(0,2) mmol/L/ano, p < 0,001] e escore de Framingham [-0,25(3,03) vs. 0,11(0,66)/por ano, p = 0,02], mas não em triglicérides [0,2(1,6) vs. 0,1(0,42) mmol/L/ano, p < 0,001] e insulinemia de jejum [1,2(5,8) vs. -0,7(2,2) UI/mL/ano, p < 0,001], comparado com o período pré-intervenção. Ocorreram reduções significativas na prevalência de glicemia de jejum alterada e tolerância à glicose diminuída após um ano de intervenção (de 58,4% para 35,4%, p < 0,001; e de 30,1% para 21,7%, p = 0,004, respectivamente). CONCLUSÕES: O programa de intervenção de um ano em hábitos de vida traz benefícios ao perfil de risco cardiometabólico em indivíduos nipobrasileiros de alto risco.

Prevalence of diabetes mellitus in the Japanese-Brazilian community of Mombuca, Guatapará, SP / Prevalência do diabetes melito na comunidade nipo-brasileira de Mombuca, Guatapará, SP

OBJECTIVE: To estimate the prevalence of type 2 diabetes mellitus (DM2) and impaired glucose tolerance (IGT) in the Japanese-Brazilian community of Mombuca in relation to risk factors (FR) for diabetes and cardiovascular disease. SUBJECTS AND METHODS: Cross-sectional study with 131 individuals of Japanese ancestry (69 percent first generation), aged 20 years or more, submitted to socio-cultural, anthropometric, and biochemistry evaluation. RESULTS: Of the individuals studied (n = 131, age = 55.1 ± 15.9 years), 58.8 percent were women. The prevalence of DM2 and IGT were 13.7 percent and 14.5 percent, respectively. Regarding RF, 76.3 percent presented dyslipidemia, 52.7 percent abdominal obesity, 48.1 percent arterial hypertension, and 42.3 percent whole body obesity. CONCLUSIONS: The prevalence of DM2, IGT, and RF in this Japanese-Brazilian community was higher than in the adult population of the city of Ribeirão Preto-SP, Brazil, suggesting an increase in risk conditions for these morbidities.

OBJETIVO: Estimar prevalências de diabetes melito tipo 2 (DM2) e tolerância à glicose diminuída (TGD) na comunidade de Mombuca, Guatapará, SP, relacionando-as com fatores de risco (FR) para diabetes e doenças cardiovasculares. SUJEITOS E MÉTODOS: Estudo transversal com 131 nipo-brasileiros (69 por cento de 1ª geração), idade > 20 anos, ambos os sexos, com avaliação sociocultural, antropométrica e bioquímica. RESULTADOS: Dos 131 participantes (idade média = 55,1 ± 15,9 anos), a maioria (58,8 por cento) era do sexo feminino. As prevalências de DM2 e TGD foram 13,7 por cento e 14,5 por cento, respectivamente. Em relação aos FR, 76,3 por cento apresentaram dislipidemia, 52,7 por cento, obesidade abdominal (OA), 48,1 por cento, hipertensão arterial (HA) e 42,3 por cento, obesidade geral. CONCLUSÕES: As prevalências de DM2, TGD e FR observadas nos nipo-brasileiros foram superiores aos valores da população adulta de Ribeirão Preto, SP, sugerindo acentuação de situações predisponentes dessas morbidades.